Relationship between COVID-19 and ICU-Acquired Bloodstream Infections Related to Multidrug-Resistant Bacteria

A bloodstream infection (BSI) is a severe ICU-acquired infection. growing proportion caused by multidrug-resistant bacteria (MDRB). COVID-19 was reported to be associated with high rate of secondary infections. However, there lack data on the relationship between and incidence MDRB BSI. The aim this study evaluate BSI related MDRB. This retrospective conducted in single-center ICU during one-year period. All adult patients admitted for more than 48 h were included. cumulative estimated using Kalbfleisch Prentice method. association status risk assessed cause-specific Cox’s proportional hazard model. Among 1320 included analysis, 497 (37.65%) had COVID-19. occurred 50 (36 COVID (7%) 14 non-COVID (1.6%)). Extended-spectrum beta-lactamase Enterobacteriacae (46%) carbapenem-resistant Acinetobacter baumannii (30%) most commonly isolated significantly higher (adjusted cHR 2.65 (1.25 5.59) whole period). only significant period starting at day 15 after admission. mortality (HR (95%CI) 1.73 (1–3)), although no impact (p het 0.94). an increased MDRB, mainly